2024-12-03 | [Review] Diagnosis and management of status epilepticus: improving the status quo | Jennifer V Gettings, Fatemeh Mohammad Alizadeh Chafjiri, Archana A Patel, Simon Shorvon, Howard P Goodkin, Tobias Loddenkemper | |
2024-11-29 | [Articles] Safety and efficacy of intravenous recombinant human prourokinase for acute ischaemic stroke within 4·5 h after stroke onset (PROST-2): a phase 3, open-label, non-inferiority, randomised controlled trial | Shuya Li, Hong-Qiu Gu, Baoyu Feng, Hao Li, Xuechun Wang, Qiang Dong, Dongsheng Fan, Yun Xu, Suiqiang Zhu, Hongguo Dai, Yan Wei, Ziran Wang, Guozhi Lu, Yutong Ma, Zixiao Li, Yilong Wang, Xia Meng, Xingquan Zhao, Liping Liu, Yongjun Wang, PROST-2 investigat | |
2024-11-29 | [Comment] Reconsidering prourokinase for acute ischaemic stroke | Guillaume Turc, Thanh N Nguyen | |
2024-11-26 | [In Context] A cautionary view on blood pressure lowering in patients with acute ischaemic stroke receiving reperfusion therapy | Nyika D Kruyt, Paul J Nederkoorn, Else Charlotte Sandset, Patrick Lyden, Lili Song, Craig S Anderson | |
2024-11-21 | [In Context] Creative neurorehabilitation: the art of intervention | Jules Morgan | |
2024-10-22 | [Personal View] Uncovering the genetic basis of Parkinson's disease globally: from discoveries to the clinic | Shen-Yang Lim, Ai Huey Tan, Azlina Ahmad-Annuar, Njideka Ulunma Okubadejo, Katja Lohmann, Huw R Morris, Tzi Shin Toh, Yi Wen Tay, Lara M Lange, Sara Bandres-Ciga, Ignacio Mata, Jia Nee Foo, Esther Sammler, Joshua Chin Ern Ooi, Alastair J Noyce, Natascha B | |
2024-10-22 | [Comment] The global dimension of Parkinson's disease genetics | Thomas Gasser | |
2024-10-14 | [Correspondence] The European expertise network for open microvascular surgery | Victor Volovici, Marco Cenzato, Torstein R Meling, EXPERVASC | |
2024-09-20 | [Articles] Safety and efficacy of memantine and trazodone versus placebo for motor neuron disease (MND SMART): stage two interim analysis from the first cycle of a phase 3, multiarm, multistage, randomised, adaptive platform trial | Suvankar Pal, Jeremy Chataway, Robert Swingler, Malcolm R Macleod, Neil O Carragher, Giles Hardingham, Bhuvaneish Thangaraj Selvaraj, Colin Smith, Charis Wong, Judith Newton, Dawn Lyle, Amy Stenson, Rachel S Dakin, Amarachi Ihenacho, Shuna Colville, Arpan | |
2024-09-20 | [Articles] Safety and efficacy of evobrutinib in relapsing multiple sclerosis (evolutionRMS1 and evolutionRMS2): two multicentre, randomised, double-blind, active-controlled, phase 3 trials | Xavier Montalban, Patrick Vermersch, Douglas L Arnold, Amit Bar-Or, Bruce A C Cree, Anne H Cross, Eva Kubala Havrdova, Ludwig Kappos, Olaf Stuve, Heinz Wiendl, Jerry S Wolinsky, Frank Dahlke, Claire Le Bolay, Li Shen Loo, Sathej Gopalakrishnan, Yann Hyver | |
2024-09-20 | [Comment] Trial designs for motor neuron disease in the 21st century | Steve Vucic | |
2024-09-20 | [Comment] Evobrutinib in multiple sclerosis: challenges and unmet goals | Anneke van der Walt | |
2024-09-19 | [Correspondence] Equitable access to levetiracetam for people with epilepsy | Arjune Sen, Neerja Chowdhary, Asma Hallab, Michele Romoli, J Helen Cross, Bernadette Cappello | |
2024-09-12 | [Personal View] Frailty for neurologists: perspectives on how frailty influences care planning | Marco Canevelli, Caitlin Jackson-Tarlton, Kenneth Rockwood | |
2024-09-12 | [Comment] Looking beyond the neurological diagnosis: considering frailty | A Jon Stoessl | |
2024-09-11 | [In Context] Learning to be an adult with a disability | Jules Morgan | |
2024-08-23 | [Correspondence] The Yaoundé Declaration | Alfred K Njamnshi, Agustin Ibanez, Gagandeep Singh, Mika Pyykko, Vladimir Hachinski, Harris A Eyre, Scientific Technical Committee | |
2024-07-27 | [Comment] Amyloid β, γ-secretase, and familial Alzheimer's disease | Marie-Claude Potier, Harald Steiner, Lucía Chávez-Gutiérrez | |
2024-07-27 | [Articles] γ-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS) | Stephanie A Schultz, Lei Liu, Aaron P Schultz, Colleen D Fitzpatrick, Raina Levin, Jean-Pierre Bellier, Zahra Shirzadi, Nelly Joseph-Mathurin, Charles D Chen, Tammie L S Benzinger, Gregory S Day, Martin R Farlow, Brian A Gordon, Jason J Hassenstab, Cliffo | |
2024-07-27 | [Articles] Endovascular thrombectomy for acute ischaemic stroke with established large infarct (TENSION): 12-month outcomes of a multicentre, open-label, randomised trial | Götz Thomalla, Jens Fiehler, Fabien Subtil, Susanne Bonekamp, Anne Hege Aamodt, Blanca Fuentes, Elke R Gizewski, Michael D Hill, Antonin Krajina, Laurent Pierot, Claus Z Simonsen, Kamil Zeleňák, Rolf A Blauenfeldt, Bastian Cheng, Angélique Denis, Hannes D | |
2024-07-27 | [Comment] Endovascular thrombectomy for large ischaemic stroke: outcomes beyond 90 days | Takeshi Morimoto, Fumihiro Sakakibara | |
2024-07-24 | [Articles] Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose study | Leonard H van den Berg, Jeffrey D Rothstein, Pamela J Shaw, Suma Babu, Michael Benatar, Robert C Bucelli, Angela Genge, Jonathan D Glass, Orla Hardiman, Vincenzo Libri, Theodore Mobach, Björn Oskarsson, Gary L Pattee, John Ravits, Christopher E Shaw, Mark | |
2024-07-24 | [Comment] Targeting C9orf72 in people with ALS | Susanne Petri | |
2024-07-23 | [In Context] On how a brain beholds beauty | Rui Araújo | |
2024-07-19 | [Correspondence] World Brain Day 2024: a focus on brain health and prevention | Wolfgang Grisold, David W Dodick, Alla Guekht, Steven L Lewis, Tissa Wijeratne | |
2024-06-28 | [Articles] Prognostic value of tissue bridges in cervical spinal cord injury: a longitudinal, multicentre, retrospective cohort study | Dario Pfyffer, Andrew C Smith, Kenneth A Weber, Andreas Grillhoesl, Orpheus Mach, Christina Draganich, Jeffrey C Berliner, Candace Tefertiller, Iris Leister, Doris Maier, Jan M Schwab, Alan Thompson, Armin Curt, Patrick Freund | |
2024-06-28 | [Review] Effects of spaceflight on the brain | Rachael D Seidler, Xiao Wen Mao, Grant D Tays, Tianyi Wang, Peter zu Eulenburg | |
2024-06-28 | [Comment] Tissue bridge widths and outcome after spinal cord injury | James Guest | |
2024-06-26 | [Review] Sleep and sleep disorders in people with Parkinson's disease | Alex Iranzo, Valerie Cochen De Cock, María Livia Fantini, Laura Pérez-Carbonell, Lynn Marie Trotti | |
2024-06-22 | [Articles] Bailout intracranial angioplasty or stenting following thrombectomy for acute large vessel occlusion in China (ANGEL-REBOOT): a multicentre, open-label, blinded-endpoint, randomised controlled trial | Feng Gao, Xu Tong, Baixue Jia, Ming Wei, Yuesong Pan, Ming Yang, Dapeng Sun, Thanh N Nguyen, Zeguang Ren, Francis Demiraj, Xiaoxi Yao, Chenghua Xu, Guangxiong Yuan, Yue Wan, Jianjun Tang, Jing Wang, Yuanfei Jiang, Chaobin Wang, Xiang Luo, Haihua Yang, Rui | |
2024-06-22 | [Comment] Bailout angioplasty or stenting for large vessel occlusion | Joanna M Roy, Stavropoula Tjoumakaris | |
2024-06-21 | [Articles] Collateral-based selection for endovascular treatment of acute ischaemic stroke in the late window (MR CLEAN-LATE): 2-year follow-up of a phase 3, multicentre, open-label, randomised controlled trial in the Netherlands | Ilse Huijberts, Florentina M E Pinckaers, Susanne G H Olthuis, Sander M J van Kuijk, Alida A Postma, Hieronymus D Boogaarts, Yvo B W E M Roos, Charles B L M Majoie, Aad van der Lugt, Diederik W J Dippel, Wim H van Zwam, Robert J van Oostenbrugge, MR CLEAN | |
2024-06-21 | [Comment] Durable benefit of thrombectomy 6–24 h after stroke onset | Bruce C V Campbell | |
2024-06-14 | [Articles] Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4·5 h of onset of ischaemic stroke (TASTE): a multicentre, randomised, controlled, phase 3 non-inferiority trial | Mark W Parsons, Vignan Yogendrakumar, Leonid Churilov, Carlos Garcia-Esperon, Bruce C V Campbell, Michelle L Russell, Gagan Sharma, Chushuang Chen, Longting Lin, Beng Lim Chew, Felix C Ng, Akshay Deepak, Philip M C Choi, Timothy J Kleinig, Dennis J Cordat | |
2024-06-14 | [Comment] Tenecteplase versus alteplase in stroke thrombolysis: the last piece of the puzzle? | Kazunori Toyoda | |
2024-06-13 | [Articles] Optimal drainage time after evacuation of chronic subdural haematoma (DRAIN TIME 2): a multicentre, randomised, multiarm and multistage non-inferiority trial in Denmark | Mads Hjortdal Grønhøj, Thorbjørn Søren Rønn Jensen, Rares Miscov, Ann Kathrine Sindby, Birgit Debrabant, Torben Hundsholt, Carsten Reidies Bjarkam, Bo Bergholt, Kåre Fugleholm, Frantz Rom Poulsen, DACSUHS group | |
2024-06-13 | [Comment] Management of subdural haematoma: optimising drainage | Amjad Elmashala, Jonathan Rosand | |
2024-06-07 | [In Context] Caring for the carers: the power of personal stories | Udani Samarasekera | |
2024-05-21 | [Articles] Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial | Michael Benatar, Thomas Hansen, Dror Rom, Marie A Geist, Thomas Blaettler, William Camu, Magdalena Kuzma-Kozakiewicz, Leonard H van den Berg, Raul Juntas Morales, Adriano Chio, Peter M Andersen, Pierre-Francois Pradat, Dale Lange, Philip Van Damme, Gabrie | |
2024-05-21 | [Comment] Amyotrophic lateral sclerosis: a lesson in translation | Orla Hardiman | |
2024-05-17 | [Articles] Specialist physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial | Glenn Nielsen, Jon Stone, Teresa C Lee, Laura H Goldstein, Louise Marston, Rachael Maree Hunter, Alan Carson, Kate Holt, Jon Marsden, Marie Le Novere, Irwin Nazareth, Hayley Noble, Markus Reuber, Ann-Marie Strudwick, Beatriz Santana Suarez, Mark J Edwards | |
2024-05-17 | [Comment] Progress in physical therapy for functional motor disorder | Mark Hallett | |
2024-05-16 | [Articles] Safety and efficacy of active blood-pressure reduction to the recommended thresholds for intravenous thrombolysis in patients with acute ischaemic stroke in the Netherlands (TRUTH): a prospective, observational, cluster-based, parallel-group st | Thomas P Zonneveld, Sarah E Vermeer, Erik W van Zwet, Adrien E D Groot, Ale Algra, Leo A M Aerden, Kees C L Alblas, Frank de Beer, Paul J A M Brouwers, Koen de Gans, H Maarten A van Gemert, Bart C A M van Ginneken, Gerke S Grooters, Patricia H A Halkes, T | |
2024-05-16 | [Comment] Challenging the management of blood pressure before intravenous thrombolysis in acute ischaemic stroke | Verónica V Olavarría | |
2024-04-20 | [Articles] Tranexamic acid versus placebo in individuals with intracerebral haemorrhage treated within 2 h of symptom onset (STOP-MSU): an international, double-blind, randomised, phase 2 trial | Nawaf Yassi, Henry Zhao, Leonid Churilov, Teddy Y Wu, Henry Ma, Huy-Thang Nguyen, Andrew Cheung, Atte Meretoja, Duy Ton Mai, Timothy Kleinig, Jiann-Shing Jeng, Philip M C Choi, Phuc Dang Duc, Helen Brown, Annemarei Ranta, Neil Spratt, Geoffrey C Cloud, Ha | |
2024-04-19 | [Corrections] Correction to Lancet Neurol 2024; 23: 393–403 | | |
2024-04-18 | [Articles] Medical management and surgery versus medical management alone for symptomatic cerebral cavernous malformation (CARE): a feasibility study and randomised, open, pragmatic, pilot phase trial | CARE pilot trial collaboration | |
2024-04-11 | [Articles] RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses | Emil K Gustavsson, Jordan Follett, Joanne Trinh, Sandeep K Barodia, Raquel Real, Zhiyong Liu, Melissa Grant-Peters, Jesse D Fox, Silke Appel-Cresswell, A Jon Stoessl, Alex Rajput, Ali H Rajput, Roland Auer, Russel Tilney, Marc Sturm, Tobias B Haack, Suzan | |
2024-04-11 | [Comment] New gene involved in the pathogenesis of Parkinson's disease | Mathias Toft | |
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